My research revolves around understanding the biomechanical changes that occur during the knee osteoarthritis disease process. Specifically, it is based on determining the joint loading changes associated with wearing an unloader brace as treatment for moderate knee osteoarthritis.
James Rioux
Physics & Space Sciences
My research focuses on imaging of cellular processes in vivo using Magnetic Resonance Imaging (MRI). While MRI is well known for its ability to produce anatomical images for clinical diagnosis, MRI can study processes on smaller scales using contrast agents such as super-paramagnetic iron oxide (SPIO). I am developing MRI techniques which will detect the presence of SPIO, and provide information about how its concentration and biodistribution change over time. This could shed light on a number of processes involving SPIO-labeled cells and molecules. For example, this could be used to monitor labeled stem cells during regenerative therapy to repair damaged spinal or cardiac tissue.
